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Childhood Risk Factors and Adult Cardiovascular Events | NEJM

Childhood Risk Factors and Adult Cardiovascular Events | NEJM

To the Editor: Jacobs et al. (May 19 issue)1 explored the association of several childhood risk factors (body-mass index [BMI], systolic blood pressure, total cholesterol level, triglyceride level, and smoking status) with vascular events in adulthood. They found that there was an association between childhood risk factors and cardiovascular events in midlife. However, neither albuminuria nor the estimated glomerular filtration rate (eGFR) was assessed. Albuminuria and a decreased eGFR are key risk factors for cardiovascular events and, together with BMI, systolic blood pressure, lipid levels, and smoking, are used in adults to assess cardiovascular risk. An elevated eGFR may indicate . . .